Biotie Therapies - Major shareholder announcements

Notification according to Chapter 9, Section 5 of the Finnish Securities Markets Act

BIOTIE THERAPIES CORP.             STOCK EXCHANGE RELEASE       June 17, 2015 at
6.45 p.m.

Notification according to Chapter 9, Section 5 of the Finnish Securities Markets
Act

Biotie Therapies Corp. (the "Company" or "Biotie") has received a notification
in accordance with Chapter 9, Section 5 of the Finnish Securities Markets Act
from Versant Ventures V, LLC on behalf of itself and Versant Venture Capital V,
L.P concerning changes in share ownership and an arrangement which, if realized,
would result in changes in share ownership.

The Company previously announced on April 24, 2015 that it had received a
notification regarding possible changes in holdings from Versant Ventures V, LLC
on behalf of itself and Versant Venture Capital V, L.P. According to the
previous notification, should the convertible promissory notes (the "Convertible
Notes") and other equity-based instruments (the "Warrants") pursuant to the
subscription agreement entered into between Biotie and certain investors be
issued to entities controlled by Versant Ventures V, LLC, their conversion and
exercise in full would have resulted in a combined holding of shares and votes
that would exceed 5 per cent.

According to the notification received today, Versant Ventures V, LLC is the
sole general partner of (i) Versant Venture Capital V, L.P., (ii) Versant
Affiliates Fund V, L.P. and (iii) Versant Ophthalmic Affiliates Fund I, L.P. and
(iv) the sole shareholder of Versant Ventures V GP-GP (Canada), Inc. Versant
Ventures V GP-GP (Canada), Inc. is the sole general partner of Versant Ventures
V (Canada), L.P., which is the sole general partner of Versant Venture Capital V
(Canada) LP. Neither Versant Ventures V, LLC nor any other entity under its
control, other than (i) Versant Venture Capital V, L.P., (ii) Versant Affiliates
Fund V, L.P., (iii) Versant Ophthalmic Affiliates Fund I, L.P. and (iv) Versant
Venture Capital V (Canada) LP, holds any shares or securities entitling to
shares in the Company.

According to the notification, the current shareholding by entities controlled
by Versant Ventures V, LLC through ordinary shares and American Depositary
Shares in the Company is as described below:

+-------------------------+-------------------------+--------------------------+
|                         |Number of shares and     |(%) of shares and voting  |
|                         |voting rights            |rights (calculated by the |
|                         |                         |Company based on the      |
|                         |                         |current number of shares) |
+-------------------------+-------------------------+--------------------------+
|Shares and voting rights |58,545,411               |5.97                      |
|currently held           |                         |                          |
+-------------------------+-------------------------+--------------------------+


The notification further refers to the Warrants, which are described in more
detail in the stock exchange release issued by the Company on April 23, 2015.
The subscription of shares based on the Warrants is conditional, among other
things, on the Warrant holder's decision to subscribe for shares and the
occurrence of certain events. To this extent, the notification concerns an
arrangement that, if realized, would result in the below described changes in
share ownership.

According to the notification, the exercise in full of the Warrants would result
in shareholdings in the Company of the entities listed in Annex 1 as described
below:

+---------------------------+---------------------------+----------------------+
|                           |Number of shares and voting|(%) of shares and     |
|                           |rights                     |voting rights         |
+---------------------------+---------------------------+----------------------+
|Shares and voting rights   |58,545,411                 |5.03                  |
|currently held             |                           |                      |
+---------------------------+---------------------------+----------------------+
|Shares that may be         |37,051,651                 |3.18                  |
|subscribed based on        |                           |                      |
|Warrants                   |                           |                      |
+---------------------------+---------------------------+----------------------+
|TOTAL                      |95,597,062                 |8.21                  |
+---------------------------+---------------------------+----------------------+


According to the notification, the total number of shares and votes used above
is 1,164,185,269, which has been calculated as (a) the current total number of
shares and votes as published by the Company in accordance with Chapter 8,
Section 6 of the Securities Markets Act (980,851,935 shares and votes), added
with (b) the total number of shares and votes following full conversion of the
Warrants (183,333,334 shares and votes), assuming no other new shares are issued
by the Company.

On the date of this release, the number of shares in Biotie Therapies Corp.
amounts to 980,851,935, of which 2,605,691 shares are held by the Company and
its subsidiaries.



In Turku, June 17, 2015

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

David Cook, CFO
Tel. +358 2 2748 900, e-mail: david.cook@biotie.com

DISTRIBUTION:

NASDAQ OMX Helsinki Ltd
Main Media
www.biotie.com



ANNEX 1: INDIRECT HOLDINGS OF SHARES AND VOTING RIGHTS

+----------------------------------------------+---------------+---------------+
|Name of shareholder and reason for indirect   |Shares         |Voting rights  |
|holding (e.g. controlled undertaking or       +----------+----+----------+----+
|transfer of voting rights)                    |Number    |%   |Number    |%   |
+----------------------------------------------+----------+----+----------+----+
|Versant Venture Capital V, L.P. (controlled by|83,891,674|7.21|83,891,674|7.21|
|Versant Ventures V, LLC)                      |          |    |          |    |
+----------------------------------------------+----------+----+----------+----+
|Versant Affiliates Fund V, L.P. (controlled by|2,523,488 |0.22|2,523,488 |0.22|
|Versant Ventures V, LLC)                      |          |    |          |    |
+----------------------------------------------+----------+----+----------+----+
|Versant Ophthalmic Affiliates Fund I, L.P.    |2,797,296 |0.24|2,797,296 |0.24|
|(controlled by Versant Ventures V, LLC)       |          |    |          |    |
+----------------------------------------------+----------+----+----------+----+
|Versant Venture Capital V (Canada) LP         |6,384,604 |0.55|6,384,604 |0.55|
|(indirectly controlled by Versant Ventures V, |          |    |          |    |
|LLC)                                          |          |    |          |    |
+----------------------------------------------+----------+----+----------+----+
|TOTAL                                         |95,597,062|8.21|95,597,062|8.21|
+----------------------------------------------+----------+----+----------+----+





[HUG#1929312]