Biotie Therapies - Company Announcement

Biotie Announces Exercise of Over-allotment Option

BIOTIE THERAPIES CORP.       STOCK EXCHANGE RELEASE              June 12, 2015
at 5.30 p.m.

Biotie Announces Exercise of Over-allotment Option

Biotie Therapies Corp. ("Biotie" or the "Company"), a specialized drug
development company focused on products for neurodegenerative and psychiatric
disorders, has received information that the underwriters have exercised their
option to subscribe for an additional 44,629 ADSs representing 3,570,320 newly
issued shares in the Company, and to purchase 519,583 ADSs from UCB S.A. solely
to cover over-allotments (the "Over-allotment Option") at the price of the U.S.
public offering. Biotie will receive gross proceeds of $664,436.55 (€589,091.72
at the fixed ECB exchange rate of $1.1279 per euro as at June 10, 2015) for the
exercise of the Over-allotment Option. Biotie will not receive any proceeds from
the ADSs sold by UCB S.A.

The Company announced on June 11, 2015 the completion of the pricing of its U.S.
public offering of 3,761,418 ADSs at a price to the public of $14.888 per ADS
for gross proceeds of $55,999,991.18 (€49,649,783.83 at the fixed ECB exchange
rate of $1.1279 per euro as at June 10, 2015). The share to ADS ratio is 80 to
one, and the ADSs will represent 300,913,440 newly issued shares in the Company
with a subscription price of €0.165 (rounded figure) per new share (at the above
mentioned fixed exchange rate).

The issuance of new shares by the Company for the purpose of the completion of
the U.S. public offering and the Over-allotment Option are based on the
authorization granted by the Annual General Meeting of shareholders on May
26, 2015. The closing of the offering of the ADSs and the issue of the new
shares for the purpose of the completion of the U.S. public offering and the
Over-allotment Option is expected to occur on or about June 16, 2015, subject to
customary closing conditions.

Biotie's shares are listed on the NASDAQ OMX Helsinki Ltd. under the symbol"BTH1V." The ADSs are trading on the NASDAQ Global Select Market as of June
11, 2015 under the symbol "BITI."

The new shares issued in the U.S. public offering (including the Over-allotment
Option) represent approximately 67 percent of the shares in the Company prior to
the U.S. public offering and the automatic conversion of the notes and
approximately 31 percent of the shares in the Company after the U.S. public
offering and the automatic conversion of the notes.

The new shares issued by the Company in the U.S. public offering and pursuant to
the Over-allotment Option, as well as due to the automatic conversion of the
notes, as announced on June 11, 2015, are expected to be registered with the
Finnish Trade Register on the date of closing of the offering of ADSs, on or
about June 16, 2015, and admitted to trading on NASDAQ OMX Helsinki Ltd. on or
about June 17, 2015. The Company will publish a prospectus for the listing of
new shares on NASDAQ OMX Helsinki Ltd. on or about June 16, 2015. The
subscription price in the U.S. public offering (including the Over-allotment
Option) and the automatic conversion of the notes will be recorded in its
entirety in the share capital of the Company.

As previously announced, Biotie intends to use the net proceeds from the
offering, together with a portion of its current liquid assets (which include
€33.1 million gross proceeds from the issue of the convertible notes) to fund
its Phase 3 double-blind clinical trial (and extension) of tozadenant in
Parkinson's through completion.

RBC Capital Markets and Stifel are acting as joint book-running managers in
connection with the offering. In addition, JMP Securities is acting as lead
manager and Roth Capital Partners is acting as co-manager.

A registration statement relating to the securities was declared effective by
the U.S. Securities and Exchange Commission on June 10, 2015. The Company has
filed a registration statement (including a prospectus) with the Securities and
Exchange Commission ("SEC") for the U.S. public offering to which this
communication relates. Before you invest in the U.S. public offering, you should
read the prospectus in that registration statement and other documents the
Company has filed with the SEC for more complete information about the Company
and this offering. You may get these documents for free by visiting EDGAR on the
SEC web site at www.sec.gov. Alternatively, the Company, any underwriter or any
dealer participating in the offering will arrange to send you the prospectus if
you request it by contacting RBC Capital Markets, LLC, 200 Vesey Street, 8th
Floor, New York, New York 10281, Attention: Equity Syndicate Department, or by
calling +1 877 822 4089, or by emailing equityprospectus@rbccm.com, or Stifel,
Nicolaus & Company, Incorporated, Attention: Syndicate, One Montgomery Street,
Suite 3700, San Francisco, California 94104, by telephone at +1 415 364 2720 or
by email at syndprospectus@stifel.com.

Turku, June 12, 2015

Biotie Therapies Corp.

Timo Veromaa
President and CEO



Contact:

Virve Nurmi, Investor Relations Manager, Biotie Therapies Corp.
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com

DISTRIBUTION:
NASDAQ OMX Helsinki Ltd
Main Media

About Biotie

Biotie is a specialized drug development company focused on products for
neurodegenerative and psychiatric disorders. Biotie's development has delivered
Selincro (nalmefene) for alcohol dependence, which received European marketing
authorization in 2013 and is currently being rolled out across Europe by partner
Lundbeck. The current development products include tozadenant for Parkinson's
disease, which is transitioning into Phase 3 development, and two additional
compounds which are in Phase 2 development for cognitive disorders including
Parkinson's disease dementia, and primary sclerosing cholangitis (PSC), a rare
fibrotic disease of the liver.

Disclaimer

The information herein may not be distributed or sent into Australia, Canada,
Japan or South Africa.

The issue, exercise and/or sale of securities in the offerings are subject to
specific legal or regulatory restrictions in certain jurisdictions. The Company
assumes no responsibility in the event there is a violation by any person of
such restrictions. Investors must neither accept any offer for, nor acquire, any
securities to which this document refers, unless they do so on the basis of the
information contained in the applicable prospectus published or offering
circular distributed by the Company.

The Company has not authorized any offer to the public of securities in any
Member State of the European Economic Area, including Finland. With respect to
each Member State of the European Economic Area, including Finland, which has
implemented the Prospectus Directive (each, a "Relevant Member State"), no
action has been undertaken or will be undertaken to make an offer to the public
of securities requiring publication of a prospectus in any Relevant Member
State. As a result, the securities may only be offered in Relevant Member States
(a) to any legal entity which is a qualified investor as defined in the
Prospectus Directive; or (b) in any other circumstances falling within Article
3(2) of the Prospectus Directive. For the purposes of this paragraph, the
expression an "offer of securities to the public" means the communication in any
form and by any means of sufficient information on the terms of the offer and
the securities to be offered so as to enable an investor to decide to exercise,
purchase or subscribe the securities, as the same may be varied in that Member
State by any measure implementing the Prospectus Directive in that Member State
and the expression "Prospectus Directive" means Directive 2003/71/EC (and
amendments thereto, including the 2010 PD Amending Directive, to the extent
implemented in the Relevant Member State), and includes any relevant
implementing measure in the Relevant Member State and the expression "2010 PD
Amending Directive" means Directive 2010/73/EU.

This communication is directed only at (i) persons who are outside the United
Kingdom or (ii) persons who have professional experience in matters relating to
investments falling within Article 19(5) of the Financial Services and Markets
Act 2000 (Financial Promotion) Order 2005 (the "Order") and (iii) high net worth
entities, and other persons to whom it may lawfully be communicated, falling
within Article 49(2) of the Order (all such persons together being referred to
as "relevant persons"). Any investment activity to which this communication
relates will only be available to and will only be engaged with, relevant
persons. Any person who is not a relevant person should not act or rely on this
document or any of its contents.

Forward-Looking Statements

This release may contain forward-looking statements regarding the proposed
timing and size of the public offering, all of which involve certain risks and
uncertainties. These statements are often, but are not always, made through the
use of words or phrases such as "believes,""anticipates,""expects,""intends,""plans,""seeks,""estimates,""may,""will,""could,""stands to,""continues,""we believe,""we intend," as well as similar expressions. Such forward-looking
statements may involve known and unknown risks, uncertainties and other factors
which might cause the actual results, financial condition, performance or
achievements of Biotie, or industry results, to be materially different from any
historic or future results, financial conditions, performance or achievements
expressed or implied by such forward-looking statements. Among the factors that
may result in differences are the inherent uncertainties associated with
competitive developments, clinical trial and product development activities,
regulatory approval requirements and estimating the commercial potential of our
product candidates. Given these uncertainties, the reader is advised not to
place any undue reliance on such forward-looking statements. These forward-
looking statements speak only as of the date of publication of this document.
Biotie expressly disclaims any obligation to update any such forward-looking
statements in this document to reflect any change in its expectations with
regard thereto or any change in events, conditions or circumstances on which any
such statement is based, unless required by law or regulation.


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