Biotie Therapies - Major shareholder announcements

Notification according to Chapter 2, Section 10 of the Finnish Securities Market Act relating to decrease in holdings

BIOTIE THERAPIES CORP. STOCK EXCHANGE RELEASE March 10, 2010 at 4.30 p.m.


Notification according to Chapter 2, Section 10 of the Finnish Securities Market
Act relating to decrease in holdings

Biotie Therapies Corp. ("Company") has gained knowledge of the notification
regarding the following changes in holdings in accordance with Chapter 2,
Section 9 of the Finnish Securities Markets Act (decrease below 1/20 of total
number of shares).

TVM Life Science Ventures VI GmbH & Co. KG has notified that their holdings has
decreased below 5% to 4.86% of total number of shares in the Company.

The holdings in accordance with Chapter 2, Section 9 of the Finnish Securities
Markets Act of which the Company has gained knowledge is described below.


 Name of the shareholder                    % of shares


 TVM Life Science Ventures VI GmbH & Co. KG         4.86%
 Register.no.HRA 84941



The registered number of shares in Biotie Therapies Corp. is 158,752,560 and the
number of voting rights attached to the shares amounts to 158,752,560. Of these
shares 463.255 are owned by the Company.

In Turku, 10 March 2010

Biotie Therapies Corp.
Timo Veromaa, President and CEO

For further information, please contact:
Virve Nurmi, Biotie Therapies Corp.
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com<mailto:virve.nurmi@biotie.com>

www.biotie.com

Distribution:
NASDAQ OMX Helsinki Ltd
Main Media





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