Biotie Therapies - Major shareholder announcements

Disclosure under Chapter 9, Section 5 of the Finnish Securities Markets Act

BIOTIE THERAPIES CORP.             STOCK EXCHANGE RELEASE       April 12, 2016
at 11.10 p.m.

Disclosure under Chapter 9, Section 5 of the Finnish Securities Markets Act

Biotie Therapies Corp. (Nasdaq Helsinki BTH1V; NASDAQ: BITI) ("Biotie" or the
"Company") has on April 12, 2016 received a notification in accordance with
Chapter 9, Section 5 of the Finnish Securities Markets Act ("SMA") from Acorda
Therapeutics, Inc. (Nasdaq: ACOR) ("Acorda").

According to the notification, the total number of Biotie shares and voting
rights owned through financial instruments by Acorda was 105.92 per cent of
Biotie's total number of shares and voting rights on April 11, 2016. According
to the notification, in accordance with the SMA and the guidelines issued by the
Finnish Financial Supervisory Authority, the notified ownership percentages
presented in the notification have been calculated against the current total
number of shares and votes published by Biotie being 1,089,608,083 (which
includes the treasury shares held by Biotie) and not taking into account the
fact that also new shares could be issued based on the warrants, option rights
and share rights, thus leading to an ownership percentage exceeding 100% of the
shares and votes in Biotie.

Total positions of Acorda subject to the notification:

+----------------------+----------------+---------------------+----------------+
|                      |% of shares and |% of shares and      |Total of both in|
|                      |voting rights   |voting rights through|% (A + B)       |
|                      |(total of A)    |financial instruments|                |
|                      |                |(total of B)         |                |
+----------------------+----------------+---------------------+----------------+
|Resulting situation on|-               |105.92               |105.92          |
|the date on which     |                |                     |                |
|threshold was crossed |                |                     |                |
|or reached            |                |                     |                |
+----------------------+----------------+---------------------+----------------+
|Position of previous  |N/A             |N/A                  |N/A             |
|notification (if      |                |                     |                |
|applicable)           |                |                     |                |
+----------------------+----------------+---------------------+----------------+

Notified details of the resulting situation on the date on which the threshold
was crossed or reached:

A: Shares and voting rights

+--------------------+----------------------------+----------------------------+
|Class/type of shares|Number of shares and voting |% of shares and voting      |
|ISIN code (if       |rights                      |rights                      |
|possible)           +---------+------------------+---------+------------------+
|                    |Direct   |Indirect          |Direct   |Indirect          |
|                    |(SMA 9:5)|(SMA 9:6 and 9:7) |(SMA 9:5)|(SMA 9:6 and 9:7) |
+--------------------+---------+------------------+---------+------------------+
|                    |-        |-                 |-        |-                 |
+--------------------+---------+------------------+---------+------------------+
|SUBTOTAL A          |                            |                            |
+--------------------+----------------------------+----------------------------+

B: Financial instruments according to SMA 9:6a

+------------+--------------+------------+------------+---------------+--------+
|Type of     |Expiration    |Exercise/   |Physical or |Number of      |% of    |
|financial   |date          |Conversion  |cash        |shares and     |shares  |
|instrument  |              |period      |settlement  |voting rights  |and     |
|            |              |            |            |               |voting  |
|            |              |            |            |               |rights  |
+------------+--------------+------------+------------+---------------+--------+
|Right and   |Confirmation  |Completion  |Physical    |1,154,064,413  |105.92  |
|obligation  |that tender   |trades April|settlement  |               |        |
|to acquire  |offer will be |14, 2016    |            |               |        |
|accepted    |completed     |Settlement  |            |               |        |
|equity      |April 11, 2016|April       |            |               |        |
|interests   |              |18, 2016    |            |               |        |
|tendered in |              |            |            |               |        |
|the tender  |              |            |            |               |        |
|offer       |              |            |            |               |        |
+------------+--------------+------------+------------+---------------+--------+
                                         |SUBTOTAL B  |1,154,064,413  |105.92  |
                                         |            |               |        |
                                         +------------+---------------+--------+

The person subject to the notification obligation is not controlled by any
natural person or legal entity and does not control any other undertaking(s)
holding directly or indirectly an interest in the (underlying) issuer.

According to the notification, Acorda announced the preliminary tender offer
results and acceptance of the equity interests tendered into Acorda's public
tender offer for all the equity interests in Biotie on 11.4.2016 and confirmed
that it will complete the tender offer in accordance with its terms and
conditions. Based on the preliminary results, the following number of equity
interests have been tendered into the tender offer:

Shares: 656,398,583;
American Depositary Shares: 3,120,541 (representing 249,643,280 shares and
votes);
Warrants: 220,400,001 (entitling to 220,400,001 shares and votes);
2011 option rights: 435,000 (entitling to 435,000 shares and votes);
2014 option rights: 4,280,125 (entitling to 7,160,125 shares and votes);
2016 option rights: 12,401,120 (entitling to 12,401,120 shares and votes);
Swiss option rights: 1,949,116 (entitling to 1,949,116 shares and votes);
2011 share rights: 25,000 (entitling to 25,000 shares and votes); and
2014 share rights: 3,972,188 (entitling to 5,652,188 shares and votes).

Further, according to the notification, the warrants, option rights and share
rights tendered into the tender offer entitle their holders to subscribe either
existing treasury shares held by Biotie (or its subsidiaries) or new shares
issued by Biotie. Based on the information published by Biotie, Biotie currently
holds 108,686,288 treasury shares.


In Turku, April 12, 2016

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Investor Relations Manager, Biotie Therapies Corp.
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com

DISTRIBUTION:

Nasdaq Helsinki Ltd
Main Media
www.biotie.com






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