Biotie Therapies - Company Announcement

Change in the number of votes relating to Biotie Therapies Corp.'s shares

Biotie Therapies Corp.          Stock Exchange Release    2 December 2011 at
11.30 a.m.

Change in the number of votes relating to Biotie Therapies Corp.'s shares

The Swiss subsidiary of Biotie Therapies Corp. ("Biotie" or the "Company"),
Biotie Therapies Holding AG (previously Synosia Therapeutics Holding AG) has
conveyed  Biotie shares  Biotie shares against consideration pursuant to the
option programs as follows:

November 2011       Total Options outstanding % of the total amount of shares
              (5-11/2011)

    1,239,816   4,735,636           9,916,151                             2.6




The conveyance of Biotie shares relates to the option plan of Synosia
Therapeutics Holding AG (currently Biotie Therapies Holding AG, "Synosia")
acquired by Biotie in February 2011. According to such Synosia share option
plan, options have been granted to employees, former directors and consultants.
In connection with the completion of the acquisition of Synosia, the option plan
was amended so that instead of shares in Synosia an aggregate maximum of
14,912,155 shares in Biotie may be subscribed based on the plan. Biotie issued
these 14,912,155 shares to its current subsidiary Synosia in connection with the
acquisition to be further conveyed to the option holders when they potentially
exercise their option rights in accordance with the terms and conditions of the
option program.

The conveyed shares previously held by the Company's subsidiary have not carried
any voting rights.  The parent company Biotie does not own any treasury shares.
The conveyance does not affect the number of registered shares.

After the conveyances the changes are as follows:

   The increase of   A total amount of     The number of the The total number of
       vote of the      voting rights:  Company's share held   registered shares
           Company                              by the Group
     November 2011                             November2011:

         1,239,816         377,417,938            10,176,519         387,594,457






Turku, 2 December 2011

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Biotie Therapies Corp.
tel. +358 2 274 8900
e-mail: virve.nurmi@biotie.com

DISTRIBUTION
NASDAQ OMX Helsinki Ltd
Main Media
www.biotie.com


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