Biotie Therapies - Notice to general meeting

INVITATION TO THE ANNUAL GENERAL MEETING OF BIOTIE THERAPIES CORP.

BIOTIE THERAPIES CORP.                 STOCK EXCHANGE RELEASE       5 April
2011 at 9.45 am

INVITATION TO THE ANNUAL GENERAL MEETING OF BIOTIE THERAPIES CORP.

Notice is given to the shareholders of Biotie Therapies Corp. to the Annual
General Meeting to be held on Friday, 6 May 2011 at 10 a.m. in an auditorium at
the Mauno Koivisto Centre, address BioCity, Tykistökatu 6, Turku, Finland. The
reception of shareholders who have registered for the meeting and the
distribution of voting tickets will commence at 9.30 a.m.

A. MATTERS ON THE AGENDA OF THE ANNUAL GENERAL MEETING

At the Annual General Meeting, the following matters will be considered:

1. Opening of the meeting

2. Calling the meeting to order

3. Election of persons to confirm the minutes and to supervise the counting of
votes

4. Recording the legality of the meeting

5. Recording the attendance at the meeting and adoption of the list of votes

6. Presentation of the financial statements, the report of the Board of
Directors and the auditor's report for the year 2010

- Review by the CEO
- The company's equity is less than a half of the share capital, if the capital
loans are not counted among the items of the company's shareholders' equity.
Possible measures to remedy the financial position of the company.

7. Adoption of the financial statements

8. Booking of the loss of the financial year

The Board of Directors proposes that loss of the financial year 2010 shall be
transferred to the unrestricted equity and no dividend shall be distributed.

9. Resolution on the discharge of the members of the Board of Directors and the
Managing Director from liability

10. Resolution on the remuneration of the members of the Board of Directors

The Board of Directors proposes on the basis of the recommendation of the
Nomination and Remuneration Committee that the remuneration payable to the
members of the Board of Directors would be as follows: EUR 4,000 per month for
the Chairman and EUR 3,000 per month for other Board members. In addition, it is
proposed that reasonable travelling expenses for the meetings would be
compensated.

11. Resolution on the number of members of the Board of Directors

The Board of Directors proposes on the basis of the recommendation of the
Nomination and Remuneration Committee that the number of members of the Board of
Directors would be ten (10).

12. Election of members of the Board of Directors

The Board of Directors proposes on the basis of the recommendation of the
Nomination and Remuneration Committee that all current members of the Board,
i.e. Peter Fellner, Bradley Bolzon, Bill Burns, Merja Karhapää, Bernd Kastler,
Ismail Kola, Guido Magni, Andrew Schwab, Piet Serrure and James Shannon would be
re-elected as members of the Board of Directors for the term expiring at the end
of the following Annual General Meeting.

13. Resolution on the remuneration of the auditors

The Board of Directors proposes on the basis of the recommendation of the Audit
Committee that the auditors' fees would be paid pursuant to a reasonable
invoice.

14. Election of auditors

The Board of Directors proposes on the basis of the recommendation of the Audit
Committee that PricewaterhouseCoopers Oy, a firm of auditors approved by the
Central Chamber of Commerce, and Mr Janne Rajalahti, Authorised Public
Accountant, would be elected as the auditors of the company.

15. Authorizing the Board of Directors to decide on the issuance of shares as
well as the issuance of options and other rights entitling to shares

The Board of Directors proposes that the Annual General Meeting would authorise
the Board of Directors to resolve on one or more issues which contains the right
to issue new shares or dispose of the shares in the possession of the company
and to issue options or other rights to the shares pursuant to chapter 10 of the
Companies Act. The authorisation would consist of up to 115,000,000 shares in
aggregate.

The authorisation would not exclude the Board of Directors' right to decide on a
directed issue. The authorisation is proposed to be used for material
arrangements from the company's point of view, such as financing or implementing
business arrangements or investments or for other such purposes determined by
the Board of Directors in which case a weighty financial reason for issuing
shares, options or other rights and possibly directing a share issue would
exist.

The Board of Directors would be authorised to resolve on all other terms and
conditions of a share issue, options and other share entitlements as referred to
in chapter 10 of the Companies Act, including the payment period, determination
grounds for the subscription price and subscription price or allocation of
shares, option or other rights free of charge or that the subscription price may
be paid besides in cash also by other assets either partially or entirely.

The authorisation would be effective until 30 June 2012. The Board of Directors
proposes that the authorisation would supersede earlier authorisations.

16. Closing of the meeting

B. DOCUMENTS OF THE ANNUAL GENERAL MEETING

The proposals relating to the agenda of the Annual General Meeting as well as
this notice are available on Biotie Therapies Corp.'s website at www.biotie.com
at the latest on 15 April 2011. In addition, the Biotie Therapies Corp.'s
financial statements, the report of the Board of Directors and the auditor's
report are available on the above-mentioned website. The proposals of the Board
of Directors and the financial statements are also available at the meeting.
Copies of these documents and of this notice will be sent to shareholders upon
request. The minutes of the meeting will be available on the above-mentioned
website as from 20 May 2011.

C. INSTRUCTIONS FOR THE PARTICIPANTS IN THE ANNUAL GENERAL MEETING

1. The right to participate and registration

Each shareholder, who is registered on 26 April 2011 in the shareholders'
register of the company held by Euroclear Finland Ltd, has the right to
participate in the Annual General Meeting. A shareholder, whose shares are
registered on his/her personal Finnish book-entry account, is registered in the
shareholders' register of the company.

A shareholder registered in the company's share register, who wants to
participate in the Annual General Meeting, shall register for the meeting no
later than 3 May 2010 at 4:00 p.m. Finnish time by giving a prior notice of
participation. Such notice can be given:

a) by e-mail to virve.nurmi@biotie.com;
b) by telephone +358 2 274 8911; or
c) by regular mail to Biotie Therapies Corp. / Virve Nurmi, Tykistökatu 6, FI-
20520 Turku, Finland.

In connection with the registration, a shareholder shall notify his/her name,
personal identification number, address, telephone number and the name of a
possible assistant or proxy representative and the personal identification
number of a proxy representative. The personal data given to Biotie Therapies
Corp. is used only in connection with the Annual General Meeting and with the
processing of related registrations.

Pursuant to chapter 5, section 25 of the Companies Act, a shareholder who is
present at the Annual General Meeting has the right to request information with
respect to the matters to be considered at the meeting.

2. Proxy representative and powers of attorney

A shareholder may participate in the Annual General Meeting and exercise his/her
rights at the meeting by way of proxy representation.

A proxy representative shall produce a dated proxy document or otherwise in a
reliable manner demonstrate his/her right to represent the shareholder at the
Annual General Meeting. When a shareholder participates in the Annual General
Meeting by means of several proxy representatives representing the shareholder
with shares at different securities accounts, the shares by which each proxy
representative represents the shareholder shall be identified in connection with
the registration for the Annual General Meeting.

Possible proxy documents should be delivered in original to the company before
the last date for registration.

3. Holders of nominee registered shares

A holder of nominee registered shares has the right to participate in the Annual
General Meeting by virtue of such shares, based on which he/she on the record
date of the Annual General Meeting, on 26 April 2011 would be entitled to be
registered in the shareholders' register of the company held by Euroclear
Finland Ltd. The right to participate in the general meeting requires, in
addition, that the shareholder on the basis of such shares has been temporarily
registered into the shareholders' register held by Euroclear Finland Ltd at the
latest by 3 May 2011 by 10:00 a.m. Such temporary registration constitutes due
registration for the Annual General Meeting.

A holder of nominee registered shares is advised to request without delay from
his/her custodian bank necessary instructions regarding the registration in the
shareholders' register of the Company, the issuing of proxy documents and
registration for the Annual General Meeting. The account management organization
of the custodian bank will register the holder of nominee registered shares, who
wants to participate in the Annual General Meeting, to be temporarily entered
into the shareholders' register of the company at the latest on 3 May 2011 at
10 a.m. Finnish time.

4. Other information

On the date of this notice to the Annual General Meeting, 5 April 2011, the
total number of shares and votes in Biotie Therapies Corp. is 387,594,457. Of
these shares, 14,912,155 are owned by Biotie Therapies Corp. and its
subsidiaries

In Turku, 5 April 2011

Biotie Therapies Corp.

Board of Directors

For further information, please contact:

Virve Nurmi, Investor Relations Manager
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com

DISTRIBUTION:
NASDAQ OMX Helsinki Ltd
Main Media


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