Biotie Therapies - Major shareholder announcements

Notification according to Chapter 2, Section 10 of the Finnish Securities Market Act

BIOTIE THERAPIES CORP. STOCK EXCHANGE RELEASE August 11, 2010 at 2.30 p.m.

Notification according to Chapter 2, Section 10 of the Finnish Securities Market
Act

Biotie Therapies Corp. ("Company") has gained knowledge of the notifications
regarding the following changes in holdings in accordance with Chapter 2,
Section 9 of the Finnish Securities Markets Act.

Pequot Capital Management, Inc (SEC-registration number 801-56015) address 187
Danbury Road, Wilton, CT 06897, United States of America ('Pequot') has notified
Company that as a result of share transactions carried out on 26 July, 2010
certain changes in holdings of the Company's shares have taken place between
various funds and trusts that are under Pequot's management.

As a result of these internal share transactions, the aggregate holdings of
Pequot remained unchanged. Though holdings by certain individual funds and
trusts changed, none of the holdings of the individual Funds did not reach,
exceed or fall below any shareholding disclosure threshold.

The changes in holdings in accordance with Chapter 2, Section 9 of the Finnish
Securities Markets Act of which the Company has gained knowledge are described
below.

Name of the          Shares prior to the    Shares after the   % of shares after
shareholder                 transactions        transactions    the transactions

Pequot Healthcare              4,688,170                   0                   0
Fund, L.P.,
187 Danbury Road,
Wilton, CT 06897,
United States of
America;

Pequot Healthcare              3,686,577                   0                   0
Offshore Fund, Inc.,
Craigmuir Chambers,
c/o Harneys
Corporate Services
Limited, PO Box 71,
Road Town, Tortola,
British Virgin
Islands;

Pequot Diversified               751,000                   0                   0
Master Fund, Ltd.,
c/o Harneys
Corporate Services
Limited, Craigmuir
Chambers, PO Box
71, Road Town,
Tortola, British
Virgin Islands;

Pequot Healthcare              1,288,406                   0                   0
Institutional Fund,
L.P
187 Danbury Road,
Wilton, CT
06897,United States
of America;

Pequot Healthcare              2,040,770                   0                   0
Emerging Markets
Master Fund, Ltd.,
Walker House, c/o
Walker SPV Limited,
Mary Street, PO Box
908GT, George Town,
Grand Cayman, Cayman
Islands

Pequot Diversified                     0             751,000               0.47%
Liquidating Trust,
c/o Wilmington Trust
Company, Rodney
Square North, 1100
North Market Street,
Wilmington, DE
19890, United States
of America

Pequot HC                              0           4,688,170               2.95%
Liquidating Trust,
c/o Wilmington Trust
Company, Rodney
Square North, 1100
North Market Street,
Wilmington, DE
19890, United States
of America

Pequot HC EM                           0           2,040,770               1.29%
Liquidating Trust,
c/o Wilmington Trust
Company, Rodney
Square North, 1100
North Market Street,
Wilmington, DE
19890, United States
of America

Pequot HC                              0           1,288,406               0,81%
Institutional
Liquidating Trust,
c/o Wilmington Trust
Company, Rodney
Square North, 1100
North Market Street,
Wilmington, DE
19890, United States
of America

Pequot HC Offshore                     0           3,686,577               2,32%
Liquidating Trust,
c/o Wilmington Trust
Company, Rodney
Square North, 1100
North Market Street,
Wilmington, DE
19890, United States
of America.

Total                         12,454,923          12,454,923              7.85 %




The registered number of shares in Biotie Therapies Corp. is 158,752,560 and the
number of voting rights attached to the shares amounts to 158,752,560. Of these
shares 463.255 are owned by the Company.

Turku, August 11, 2010

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Biotie Therapies Corp.
tel. +358 2 274 8900
e-mail:virve.nurmi@biotie.com

DISTRIBUTION
NASDAQ OMX Helsinki Ltd
Main Media
www.biotie.com



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