Biotie Therapies - Company Announcement

Directed offer of treasury shares in Biotie Therapies Corp. pursuant to Standby Equity Distribution Agreement

BIOTIE THERAPIES CORP.   STOCK EXCHANGE RELEASE 8 December 2010 at 9:00 a.m.

Directed offer of treasury shares in Biotie Therapies Corp. pursuant to Standby
Equity Distribution Agreement

The Board of Directors of Biotie Therapies Corp. has decided to offer 1,493,875
treasury shares to YA Global Master SPV Ltd, a fund managed by Yorkville
Advisors, LLC, through a directed share offer against cash payment of EUR
500,000 pursuant to a Standby Equity Distribution Agreement ("SEDA") as
announced on 23 October 2009.

The subscription price of EUR 0.33 per share was determined by the Board of
Directors on the basis of the volume-weighted average price of Biotie's share in
the trading on the NASDAQ OMX Helsinki stock exchange during the period from 30
November to 7 December 2010 in the manner determined in the SEDA. The
subscription price corresponds to 95 % of the share price of the closing price
of the company's shares determined in the trading on 7 December 2010.

The offer is made in order to strengthen Biotie's working capital and to provide
further financing for the company's R&D programs.

Biotie has already offered 2,967,542 treasury shares pursuant to the SEDA with
Yorkville as announced on 23 October 2009.

The shares are offered based on the authorisation by the General Meeting of
Shareholders of Biotie held on 15 April 2010. The subscription price of the
offered shares will be registered in its entirety to the share capital of
Biotie. Biotie now has 161,256,847 shares outstanding and holds additional
14,747,084 treasury shares after the transfer.

Evli Bank Plc acts as lead arranger to Biotie regarding the execution of the
SEDA.

In Turku, 8 December 2010

Biotie Therapies Corp.
The Board of Directors

For further information, please contact:
Virve Nurmi, Investor relations manager.
tel. +358 2 274 8900
e-mail:virve.nurmi@biotie.com
www.biotie.com

DISTRIBUTION:

NASDAQ OMX Helsinki Ltd
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