Biotie Therapies - Major shareholder announcements

Disclosure under Chapter 9, Section 5 of the Finnish Securities Markets Act

BIOTIE THERAPIES CORP.             STOCK EXCHANGE RELEASE       April 20, 2016
at 4.30 p.m.

Disclosure under Chapter 9, Section 5 of the Finnish Securities Markets Act

Biotie Therapies Corp. (Nasdaq Helsinki BTH1V; NASDAQ: BITI) ("Biotie" or the
"Company") has on April 20, 2016 received a notification in accordance with
Chapter 9, Section 5 of the Finnish Securities Markets Act, according to which
the holding of Invesco Limited in Biotie's shares has fallen below the threshold
of 5 per cent on April 19, 2016.

Biotie's registered total number of shares and voting rights amounting to
1,089,608,083 has been used in the calculation of percentages for the
announcement.

Total positions of Invesco Limited subject to the notification:

+-----------------------+----------------+---------------------+---------------+
|                       |% of shares and |% of shares and      |Total of both  |
|                       |voting rights   |voting rights through|in % (A + B)   |
|                       |(total of A)    |financial instruments|               |
|                       |                |(total of B)         |               |
+-----------------------+----------------+---------------------+---------------+
|Resulting situation on |-               |-                    |-              |
|the date on which      |                |                     |               |
|threshold was crossed  |                |                     |               |
|or reached             |                |                     |               |
+-----------------------+----------------+---------------------+---------------+
|Position of previous   |7.74            |N/A                  |7.74           |
|notification (if       |                |                     |               |
|applicable)            |                |                     |               |
+-----------------------+----------------+---------------------+---------------+

Notified details of the resulting situation on the date on which the threshold
was crossed or reached:

A: Shares and voting rights

+-----------------------+---------------------------+--------------------------+
|Class/type of shares   |Number of shares and voting|% of shares and voting    |
|ISIN code (if possible)|rights                     |rights                    |
|                       +---------+-----------------+---------+----------------+
|                       |Direct   |Indirect         |Direct   |Indirect        |
|                       |(SMA 9:5)|(SMA 9:6 and 9:7)|(SMA 9:5)|(SMA 9:6 and    |
|                       |         |                 |         |9:7)            |
+-----------------------+---------+-----------------+---------+----------------+
|Shares                 |-        |-                |-        |-               |
|(FI0009011571)         |         |                 |         |                |
+-----------------------+---------+-----------------+---------+----------------+
|                       |         |                 |         |                |
+-----------------------+---------+-----------------+---------+----------------+
|SUBTOTAL A             |-                          |-                         |
+-----------------------+---------------------------+--------------------------+



B: Financial instruments according to SMA 9:6a

+--------------+--------------+--------------+-------------+---------+---------+
|Type of       |Expiration    |Exercise/     |Physical or  |Number of|% of     |
|financial     |date          |Conversion    |cash         |shares   |shares   |
|instrument    |              |period        |settlement   |and      |and      |
|              |              |              |             |voting   |voting   |
|              |              |              |             |rights   |rights   |
+--------------+--------------+--------------+-------------+---------+---------+
|-             |-             |-             |-            |-        |-        |
+--------------+--------------+--------------+-------------+---------+---------+
|              |              |              |             |         |         |
+--------------+--------------+--------------+-------------+---------+---------+
                                             |SUBTOTAL B   |-        |-        |
                                             +-------------+---------+---------+


This disclosure has been made as a result of Acorda Therapeutics' voluntary
tender offer for all of the issued and outstanding shares in Biotie Therapies
Corp.


In Turku, April 20, 2016

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Investor Relations Manager, Biotie Therapies Corp.
tel. +358 2 274 8900, e-mail: virve.nurmi@biotie.com

DISTRIBUTION:

Nasdaq Helsinki Ltd
Main Media
www.biotie.com






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