Biotie Therapies - Total number of voting rights and capital

Change in the number of votes relating to Biotie Therapies Corp.'s shares

Biotie Therapies Corp.        Stock Exchange Release    November 2, 2015 at
9.00 a.m.

Change in the number of votes relating to Biotie Therapies Corp.'s shares

Biotie Therapies Corp. (Nasdaq Helsinki BTH1V; NASDAQ: BITI) ("Biotie" or the"Company") announces that the Swiss subsidiary of   the Company, Biotie
Therapies AG (previously Synosia Therapeutics Holding AG and Biotie Therapies
Holding AG) has conveyed Biotie shares against consideration pursuant to the
option programs as follows:

 October 2015 to date Total (5/2011-   Options
                      10/2015 to date) outstanding

 7,739                9,802,616        2,027,628


The conveyance of Biotie shares relates to the option plan of Synosia
Therapeutics Holding AG (currently Biotie Therapies Holding AG, "Synosia")
acquired by Biotie in February 2011. According to such Synosia share option
plan, options have been granted to employees, former directors and consultants.
In connection with the completion of the acquisition of Synosia, the option plan
was amended so that instead of shares in Synosia an aggregate maximum of
14,912,155 shares in Biotie may be subscribed based on the plan. Biotie issued
these 14,912,155 shares to its current subsidiary Synosia in connection with the
acquisition to be further conveyed to the option holders when they potentially
exercise their option rights in accordance with the terms and conditions of the
option program.

The conveyed shares previously held as Treasury shares have not carried any
voting rights. The conveyance does not affect the number of registered shares.

After the conveyances the changes are as follows:

 Increase in number of      Total amount of Number of the         Total number
 outstanding shares         voting rights    Company's share held of registered
                                             by the Biotie Group  shares

 7,739                      978,253,983     108,686,288           1,086,940,271




Turku,  November 2, 2015

Biotie Therapies Corp.

Timo Veromaa
President and CEO

For further information, please contact:

Virve Nurmi, Biotie Therapies Corp.
tel. +358 2 274 8900
e-mail: virve.nurmi@biotie.com

DISTRIBUTION
NASDAQ OMX Helsinki Ltd
Main Media
www.biotie.com


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